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Exactly how long can Mounjaro be out of the fridge

In simple terms, it means using smaller doses than the recommended starting dose, or not escalating the dosing until you reach a maintenance dose (which is the standard practice used in clinical trials)

At refrigerator temperatures (2 to 8 degrees Celsius), the degradation reactions slow to a crawl

A separate trial (ATTAIN-MAINTAIN) tested whether people who had already lost weight on injectable Wegovy or Mounjaro could maintain that weight loss by switching to oral orforglipron

Consequently, in patients initiating GLP-1 receptor agonists or dual GLP-1/GIP agonists, lipid-lowering and antihypertensive therapies should also be optimised in those not already at target, as the effects of GLP-1-based therapies alone are unlikely to be sufficient to achieve these goals